Objective:To observe the clinical effect of Qingning tablet combined with thirteen ghosts in the treatment of insomnia after stroke .Methods:60 patients with insomnia after stroke were randomly divided into ex-perimental group and control group (n = 30) .The experimental group was treated with Qingning tablet combined with thirteen ghosts and the control group was treated with estazolam .After 4 weeks of treatment ,PSQI score was performed to observe the clinical efficacy .Results :The effective rate of PSQI score was 93 .33% in the experimental group and 86 .67% in the control group .The difference was statistically significant (Z = 2 .261 , P<0 .05) .After treatment ,the scores of PSQI and the factor scores of the two groups were significantly decreased compared with those before treatment .The scores of PSQI and sleep quality ,sleep disorders ,hypnotic drugs and daytime function-al factors were significantly lower in the experimental group than those in the control group (P<0 .05) .The inci-dence of adverse reactions was 3 .33% (1/30) in the experimental group and 23 .33% (7/30) in the control group , the difference was statistically significant (χ2 = 3 .606 ,P<0 .05) .Conclusion :The threeteen ghosts combined with Qingning tablet can significantly improve the insomnia symptoms of stroke patients ,and the improvement of sleep quality ,sleep quality and daytime quality of life is more obvious and less adverse reactions .%目的 :观察清宁片结合十三鬼穴治疗中风后失眠的临床疗效.方法:将60例中风后失眠患者随机分为试验组和对照组各30例,试验组给予清宁片结合十三鬼穴治疗,对照组给予艾司唑仑治疗.治疗4周后进行PSQI评分,观察临床疗效.结果:试验组PSQI评分有效率达93.33%,对照组有效率为86.67%,两组差异具有统计学意义(Z=2.261,P<0.05).治疗后两组患者PSQI总分及各因子评分与治疗前比较均明显下降,试验组PSQI总分及睡眠质量、睡眠障碍、催眠药物、日间功能因子评分明显低于对照组,差异具有统计学意义(P<0.05).试验组不良反应发生率为3.33%(1/30),对照组为23.33%(7/30),比较差异具有统计学意义(χ2=3.606,P<0.05).结论:十三鬼穴结合清宁片能显著改善中风患者的失眠症状,对于入睡、睡眠质量及生活质量的改善较显著.
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