MR全身DWI的可重复性研究

摘要

Objective:To investigate the repeatability of magnetic resonance whole-body diffusion weighted imaging (WB-DWI).Methods:33 cases of healthy volunteers (13 men and 20 women,age range 42～76 years,mean age 52.3 years) were recruited who underwent WB-DWI examination during February 2008 to April 2012.All volunteers underwent twice WB-DWI scan (inspection intervals range 71 days to 405 days,average interval 237.4 days).The overall scoring of WBDWI graphics and the measurement of part parameters in twice examinations were done respectively.All the obtained data were analyzed with Paired-Sample t test Results:The scorings of imaging evaluation within twice WB-DWI for the same volunteers were not statistically significant (t-value =0.571,P =0.572) ; There were not statistically significant (P＞0.05) differences of ADC value,eADC values,the SI value in b=600s/mm2 and the SI value in b=0s/mm2 in splenium of corpus callosum,white matter of left temporal lobe and occipital lobe,liver,spleen,right kidney and left kidney,between the twice checkings.Conclusion:In terms of overall image evaluation or internal parameters measurement between twice WB-DWI scans done on the same volunteers,all results illustrate good repeatability for the WB-DWI scan,this provides evidence for clinical and research.%目的:探讨MR全身DWI的可重复性.方法:搜集行MR全身DWI(WB-DWI)检查的33例健康志愿者,所有志愿者均行两次WB-DWI检查,两次检查间隔时间为71～～405d,平均间隔时间为237.4d;分别对每位患者两次WB-DWI检查的图像进行评分,测量相关兴趣区的ADC值、eADC值及信号值(SI),并进行统计学分析.结果:两次检查图像评分分别为(58.303±1.489)和(58.091±1.508)分,差异无统计学意义(P＞0.05)；同一检查者的胼胝体压部、左侧颞枕白质、肝脏、脾脏、右肾、左肾区域两次检查测得的ADC值、eADC值、SI值差异均无统计学意义(P＞0.05).结论:同一志愿者前后两次行WB-DWI检查,无论是图像整体评价还是参数值测量,均具有很好的可重复性,为WB-DWI应用于临床和研究提供了依据.