100kVp条件下头颈CTA检查中碘克沙醇（270mgI／mL）个性化注射方案的成像效果初探

摘要

Objective:To evaluate the feasibility of head and neck CTA with 100kVp technique and individualization protocol of Iodixanol (270 mg I/mL)administration.Methods:50 patients underwent head and neck CTA using Iodixanol (270mg I/mL)as contrast medium.The individual contrast medium protocol were as follows:total volume of contrast medium administrated= weight(kg)×0.5mL/kg.According to different time period of injection,which were 7s,8s and 9s, these patients were divided into 3 groups (Group A,Group B,Group C respectively);the injection rate= volume/injection time,with the highest rate as 6mL/s.Using smart tracing trigger technique for contrast injection,the region of interest (ROI)was placed at aortic arch,the threshold was set as 80HU.The reformatted images were subjectively evaluated by 2 radiologists with 5 scale method,and the CT values of carotid artery and intra-cerebral artery were measured.Results:There were no significant statistic differences in gender,age and BMI among the 3 groups (P>0.05).The image quality scores of Group A,Group B and Group C was 4.75±0.41、4.85±0.34 and 4.29±0.61 respectively,no statistic difference was existed between Group A and Group B (P>0.05),significant statistic difference was existed between Group A,Group B and Group C (P= 0.004 and 0.024 respectively).Of the CT values of carotid arteries and intra-cerebral arteries of the 3 groups,no statistic difference was showed between Group A and Group B (P>0.05),yet there were significant differences between Group A,Group B and Group C (P= 0.001 and 0.037 respectively).Conclusion:Individualization of injection pro-tocol is feasible in head and neck CTA with iodixanol (270mg I/mL).The image quality can meet the requirement of diagnosis.%目的：探讨100 kVp 条件下、头颈部 CTA 检查中碘克沙醇（270 mg I/mL）个性化注射方案的成像效果。方法：连续50例患者行头颈部CTA 检查。使用对比剂碘克沙醇（270 mg I/mL ），个性化对比剂注射方案如下：注射总量＝体重（kg）×0．5 mL/kg；根据注射时间的不同（分别为7、8和9 s）将患者分为3组（依次为A、B、C组）；注射流率＝注意总量/注射时间，规定最高流率为6 mL/s；采用对比剂智能跟踪触发技术，兴趣区置于主动脉弓处，阈值为80 HU。由两位阅片者对3组的重组图像进行主观评估（5分法），并测量颈部及脑内动脉的CT值。结果：三组患者的年龄、性别、身体质量指数（BMI）的差异无统计学意义（P＞0．05）。三组图像的主观评分分别为4．75±0．41、4．85±0．34和4．29±0．61， A组与B组主观评分的差异无统计学意义（P＞0．05），A 组、B 组与 C 组间主观评分的差异有统计学差异（P＝0．004、0．024）。三组图像上颈动脉及脑内动脉的CT值：A组与B组间CT值的差异无统计学意义（P＞0．05），A组、B组与C组间CT值的差异有统计学差异（P＝0．001～0．037）。结论：碘克沙醇（270 mg I/mL）在头颈CTA 检查中可进行个性化注射，图像质量可满足诊断需求。