Rh催化的5+2反应及其在有机合成中的应用

摘要

Rh催化的[5+2]反应是一类高效快速构筑多官能团化七元环的重要方法。介绍了常用的Rh催化剂及其配体；分别基于乙烯基环丙烷(VCP)和劳腾施特劳赫中间体类型的Rh催化[5+2]反应；Rh催化的[5+2]反应机理；Rh催化的[5+2]反应在复杂天然产物合成中的应用。%The rhodium-catalyzed [5+2] cycloaddition reaction is an important methodology in rapid and efficient synthesis of a variety of multifunctional seven-membered ring. Introduced in this review were common rhodium-catalysts, catalyzed [5+2] cycloaddition reactions, the mechanism involved and potential applications in the synthesis of natural products.