脑出血后并发迟发性脑水肿的危险因素分析

摘要

Objective To analyze the risk factors for cerebral hemorrhage complicated with delayed cerebral edema.Methods We selected 120 patients with late-onset cerebral edema after cerebral hemorrhage from March 2013 to August 2016 in our hospital as observation group.Another 120 patients without late-onset cerebral edema after cerebral hemorrhage during the same period were selected as control group.The basic information,medical history and NIHSS score,blood glucose,fibrinogen,blood loss and MMP-9 level were compared between the two groups.Results In the observation group,the numbers of patients with history of smoking and hypertension,NIHSS score,blood glucose,fibrinogen,blood loss and the level of MMP-9 were significantly higher when compared to the control group (P ＜ 0.05).The multi-factor Logistic regression analysis showed that the NIHSS score,blood glucose,fibrinogen,blood loss and MMP-9 are all risk factors affecting the concurrency of late-onset cerebral edema after cerebral hemorrhage.Conclusion NIHSS score,blood glucose,fibrinogen,blood loss and MMP-9 are risk factors for late-onset cerebral edema after cerebral hemorrhage.We should pay an attention in clinics%目的 分析脑出血后并发迟发性脑水肿的危险因素.方法 选取2013年3月至2016年8月我院收治的脑出血后并发迟发性脑水肿患者120例(观察组),同期脑出血后未并发迟发性脑水肿患者120例(对照组).比较两组基本资料、既往病史及NIHSS评分、血糖、纤维蛋白原、出血量、基质金属蛋白酶9(MMP-9)水平.结果 观察组吸烟例数、高血压史例数、NIHSS评分、血糖、纤维蛋白原、出血量、MMP-9水平均高于对照组(均P＜0.05).NIHSS评分、血糖、纤维蛋白原、出血量、MMP-9为影响脑出血后并发迟发性脑水肿的危险因素.结论 脑出血后并发迟发型脑水肿的危险因素包括NIHSS评分、血糖、纤维蛋白原、出血量、MMP-9,应引起临床重视.