经直肠超声对前列腺恶性肿瘤诊断的临床应用研究

摘要

Objective To evaluate the clinical value of transrectal ultrasound in the diagnosis of prostate malignant tumor. Methods Transrectal ultrasound was used to examine 218 patients with abnormal serum PSA or digital rectal examination, compared with the pathologic diagnosis of biopsy. Results Transrectal ultrasound showed 145 cases of prosrate cancer out of 218 patients, including 76 cases of abnormal nodules, 77 cases of diffuse lesions. Biopsy confirmed 76 cases of prostate cancer, 3 cases of high-grade prostatic intra-epithelial neoplasia, 1 case of prostate neuroendocrine tumor.The coincidence rate of ultrasound and pathology was 50. 00％. The sensitivity of transrectal ultrasound in diagnosing prostare malignant tumor was 72. 5％, and the specificity was 36. 96％. Conclusions Transrectal ultrasound is an important method in the diagnosis of prostate malignant tumor,which can increase the detection rate of prostate malignant tumor.%目的 探讨经直肠超声诊断前列腺恶性肿瘤的临床价值.方法 对218例血清前列腺特异性杭原(PSA)异常或直肠指检异常的患者行经直肠超声检查,通过与系统穿刺活检病理的比较,评价经直肠超声诊断前列腺恶性肿瘤的临床意义.结果 218例患者中,经直肠超声提示前列腺癌可能者145例,穿刺活检病理证实前列腺癌76例,高级别前列腺上皮内瘤变3例,前列腺神经内分泌肿瘤1例;超声与病理的符合率为50.00%;经直肠超声诊断前列腺恶性肿瘤的灵敏度为72.5%,特异度为36.96%.结论 经直肠超声是诊断前列腺恶性肿瘤的重要方法,可提高前列腺恶性肿瘤的检出率.