Objective To investigate the related clinical and pathologic factors of gastrointestinal stromal tumor (GIST) in the elderly. Methods The clinical data of 44 elderly patients with GIST were analyzed with Kaplan-Meier method and Cox regression model. Results The results of Kaplan-Meier method showed that the prognosis of GIST was related to location, tumor size, milotic count and grade criteria of biological behavior, and tumor size, mitotic count and grade criteria of biological behavior were the independent prognosis-associated factors according to Cox regression model. Conclusions The prognostic analysis of elderly patient with GIST is helpful to the treatment, and is favorable to eliminate the risk factors affecting the prognosis.%目的 探讨老年胃肠道间质瘤(GIST)预后相关的临床及病理因素. 方法 根据Kaplan-Meier 法和Cox比例风险模型对收集到的44例GIST老年患者的预后与相关临床及病理因素进行回顾性评估分析.结果 根据Kaplan-Meier法单因素分析得知GIST的预后与肿瘤的生长部位、大小、核分裂像,以及GIST的生物学行为分级标准有关.根据多因素分析Cox比例风险模型得知肿瘤的大小、核分裂像、GIST的生物学行为分级标准是独立的预后因素. 结论 老年GIST患者的预后分析帮助制定患者的治疗策略,并有利于消除影响预后的危险因素.
展开▼
