Objective To review the irrational use of prophylactic application of antibiotics during perioperative in patients undergoing 3 kinds of clean surgery (thyroid surgery, breast surgery, or herniorrhaphy) , and to provide suggestions on rational use of antibiot ics. Methods The prophylactic application of antibiotics during perioperative in patients undergoing 3 kinds of clean surgery in 2010 including 836 cases were investigated retrospectively. Results The utilization ratio of antibiotics in 3 kinds of clean surgery reached 100%. The utilization ratio of cephalosporins was the highest among the all kinds of antibiotics, the next was fluoroquinolone. The duration of taking antibiotics was over 7 days after the surgeries. Conclusion There are some problems on prophylactic application of antibiotics in perioperative period. The concept of the rational preventive use of antibiotics during perioperative period should be strengthened.%目的 通过总结3种清洁手术围手术期抗菌药物使用不合理现象,为规范围手术期应用抗菌药物提供建议.方法 对2010年普外科3种清洁手术(甲状腺、乳腺和疝气)836例围手术期抗菌药物应用进行回顾性分析.结果 836例3种清洁手术抗菌药物应用率为100%,头孢菌素类药物使用率最高,其次为喹诺酮类,术后用药时间>7 d.结论 3种清洁手术在围手术期抗菌药物的使用中存在着不合理现象,应强化围手术期预防性应用抗菌药物的合理化意识.
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