提高研发成功率——基于模型的药物开发概念与应用

摘要

药物开发过程中面临一系列的挑战与机遇,临床药物开发时间长,失败率高.药物与疾病模型能够帮助我们将试验数据转化为知识,为药物开发提供定量基础,为研发过程中的监管决策提供参考.%In the process of drug development,there are a series of challenges and opportunities.The clinical drug development is long with a high rate of failure.Drug and disease model can help us transform experimental data into knowledge.It provided quantitative basis for drug development.It also provided references for regulatory decisions in the process of drug R&D.