三氟苯嘧啶的合成与杀虫活性研究

摘要

三氟苯嘧啶为杜邦公司开发的新型介离子类杀虫剂.以2-氨基吡啶、间三氟甲基苯乙酸等为起始原料,经过6步反应合成三氟苯嘧啶.目标化合物结构经1H NMR确证.杀虫活性测试结果表明:三氟苯嘧啶对小菜蛾、黏虫、桃蚜均具有一定的活性.在100 mg/L质量浓度下,三氟苯嘧啶对桃蚜的致死率达到89.1％.%Triflumezopyrim was a novel mesoionic insecticide developed by DuPont.Triflumezopyrim was synthesized from 2-aminopyridine and 3-(trifluoromethyl)phenylacetic acid.The structure of the target compound was confirmed by 1H NMR.The results of insecticidal activity at greenhouse showed that triflumezopyrim had insecticidal activities against diamondback moth,army worm and green peach aphid.At the concentration of 100 mg/L,the mortality of triflumezopyrim against green peach aphid was 89.1％.