ADM包扎治疗烧烫伤Ⅱ度创面临床效果的观察

摘要

Objective To investigate the clinical effect of ADM ( Heterogeneous Acellular dermal matrix) on the treatment of burn wounds in the second degree burn. Methods 50 patients were randomly divided into treatment group and control group with or without the use of the Heterogeneous Acellular dermal matrix ( treatment group) . The difference of the two groups in the change of the pain, the number of dressing change, and the prognosis of scar hyperplasia were compared. Results In the treatment group, patients with group 0 class I pain were 22 cases ( 44%) when admission. There were 48 cases ( 96%) after treatment and the difference was statistically significant (P<0.01);In control group, patients with group 0 class I pain on admission were 23 cases (46%). There were 20 cases (40%) after treatment and the difference was not statistically significant (P>0.05). In the two groups after treatment, there was significant difference in 0-I grade pain rate ( P<0.01) . The patients in the treatment group were lighter and more flexible than the control group. After six months, there were significant difference in wound scar formation (P<0.01). Conclusion Xenogenic deproteinization A⁃cellular Dermal Matrix for treating second degree burn wound can relieve pain quickly, promote wound healing, reduce scar hyperplasia, alleviate the suffering of patients, reduce doctor amount of labor and so on. ADM is one of the ideal inner layer dressing.%目的：探讨异种脱细胞真皮基质（ ADM）包扎治疗烧烫伤Ⅱ度创面的临床效果。方法随机采用ADM包扎治疗（观察组）和使用磺胺嘧啶银乳膏包扎治疗（对照组）的烧烫伤Ⅱ度创面各50例。比较两组在换药后疼痛、换药次数、预后瘢痕增生等方面的差异。结果观察组0～Ⅰ级疼痛入院时22例（44％），治疗后48例（96％），差异具有统计学意义（P＜0．01）；对照组0～Ⅰ级疼痛入院时23例（46％），治疗后20例（40％），差异无统计学意义（P＞0．05）。两组治疗后0～Ⅰ级疼痛率比较，差异有统计学意义（ P＜0．01）。观察组患者创面愈合后皮肤颜色比对照组颜色更浅、弹性更好。半年后创面瘢痕形成有明显差异（ P＜0．01）。结论 ADM治疗烧烫伤Ⅱ度创面具有止痛快、促进创面愈合，减少瘢痕增生，减轻患者痛苦，减少医生劳动量等优点。