Objective To comprehensively evaluate the risk factors in Chinese population with cerebral stroke by Meta analysis. Methods Clinical data of the risk factors in patients with cerebral stroke from January to June 2003 un-derwent Meta analysis with case-control literature abroad and in China. Results The 8 pieces of research articles includ-ed 5416 cases and 10 473 control cases. The odds ratios ( OR) of hypertension, diabetes, heart disease, atherosclerosis, hyperlipidemia, family history, history of smoking and alcohol drinking were all higher than 1, and there were significant differences (P<0. 05);the 95% confidence intervals of gender and obesity all included 1, but the relations with stroke could not be confirmed;hypertension percentage of attributable risk was the highest (69. 16%). Conclusion Risk fac-tors in Chinese population with cerebral stroke are hypertension, heart disease, diabetes, hyperlipidemia, atherosclero-sis, smoking, alcohol drinking and family history as the current evidence shows.%目的：运用meta分析方法综合评价中国人群脑卒中的发病危险因素。方法对2003年1月-2012年6月国内发表的有关中国人群脑卒中发病危险因素的研究文献进行meta分析。结果本研究共纳入8篇文献,累计病例5416例,对照10473例。危险因素中高血压病、糖尿病、心脏病、动脉粥样硬化、高脂血症、家族史、吸烟和饮酒的比值比(OR)均>1,差异有统计学意义(P<0.05)；性别和肥胖的95%可信区间均包含1,尚不能确定其与脑卒中的关系；高血压病的归因危险度最高(69.16%)。漏斗图分析：高血压病和糖尿病存在发表性偏倚；敏感性分析：家族史为脑卒中发病危险因素的稳定性较差。结论现有证据表明,高血压病、心脏病、糖尿病、高脂血症、动脉粥样硬化、吸烟、饮酒和家族史是中国人群脑卒中发病的危险因素。
展开▼
