Objective To investigate effect of Qijiaoshengbai Capsule on bone marrow depression in prevention of patients with head and neck cancer after radiotherapy.Methods A total of 86 patients with head and neck cancer admitted during January 2012 and May 2016 were divided into control group and observation group (n =43 for each group) according to therapeutic method.All patients were treated with routine treatment and radiotherapy for head and neck tumors,and observation group was treated with Qijiaoshengbai Capsule on the basis of the above treatments.After treatment,results of routine blood test,myelosuppression and incidence rates of adverse reaction at different time points after treatment were observed in two groups.Results Numbers of decreased white blood cell and neutrophilic granulocyte in observation group were significantly lower than those in control group (P ＜ 0.05),and incidence rates of myelosuppression at different time points after chemotherapy in observation group were significantly lower than those in control group (P ＞ 0.05).There was no significant difference in incidence rate of adverse reaction between two groups (P ＞ 0.05).Conclusion Qijiaoshengbai Capsule for preventive use can significantly reduce incidence rate of myelosuppression of patients with head and neck cancer after radiotherapy with good safety.%目的 探讨预防应用芪胶升白胶囊对头颈部肿瘤患者放疗后骨髓抑制的影响.方法 选取2012年1月-2016年5月收治的86例头颈部肿瘤患者,按治疗方法分为对照组和观察组,每组43例.所有患者均予头颈部肿瘤常规放疗,观察组在此基础上加用芪胶升白胶囊治疗.观察治疗结束后2组血常规及治疗后不同时间骨髓抑制及不良反应发生情况.结果 观察组白细胞和中性粒细胞减少程度优于对照组,化疗结束后不同时间骨髓抑制发生率低于对照组(P＜0.05).2组不良反应发生率比较差异无统计学意义(P＞0.05).结论 预防使用芪胶升白胶囊可明显降低头颈部肿瘤放疗后骨髓抑制发生率,且安全性较高.
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