目的：：观察甲状腺激素水平与不同病因导致患者慢性心力衰竭程度的相关性。方法：150例慢性心力衰竭患者作为心衰组，根据病因不同再分为3个亚组即，高血压导致心衰组，陈旧心肌梗死导致心衰组，其他原因如风湿性心脏病、扩张性心肌病等导致心衰组，每组各50例。选取健康体检者50例作为对照组。应用化学发光法测定心衰组患者和对照组体检者的血清三碘甲状腺氨酸(T3)、甲状腺素(T4)、血清游离三碘甲状腺原氨酸(FT3)、游离四碘甲状腺原氨酸(FT4)及促甲状腺激素(TSH)值，比较各组间的差异。结果：心衰组患者 T3、FT3含量明显低于对照组，并且随着心衰的加重 T3、FT3渐下降，有统计学意义；而 FT4、T4、TSH 无差异。心衰组患者之间，每两组比较 T3、FT3下降程度上无显著差异。结论：T3、FT3水平下降程度与慢性心功能衰竭的严重程度存在相关性。%Objective: To observe correlations of thyroid hormone level and severity of heart failure caused by different causes. Methods: 150 cases with heart failure were used as heart failure group and then could be divided into three subgroups, including hy-pertensive heart failure group, old myocardial infarction heart failure group and other heart failure group (rheumatic heart disease, di-lated cardiomyopathy and the like), with 50 cases in each subgroup. 50 healthy controls were selected as control group. The levels of T3, T4, FT3, FT4, TSH of the two groups were determined by chemiluminescence. The differences were compared between these groups. Results: The contents of T3 and FT3 of heart failure group were significantly lower than those of control group. It had been found that T3 and FT3 contents were gradually decreased as heart failure aggravated, and the differences were statistically significant. The contents of T4, FT4, and TSH had no significant differences. The comparison between the subgroups, there were no significant differences in the decrease degrees of T3 and FT3. Conclusions: There is a correlation between the decrease degrees of T3 and FT3 and severity of heart failure.
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