18F-FDG PET-CT显像在妇科恶性肿瘤复发中的应用价值探讨

摘要

目的：探讨18F-FDG PET-CT显像在妇科恶性肿瘤复发中的临床应用价值。方法：选取经过本院确诊的30例妇科恶性肿瘤患者，分为两组，第一组10例，治疗后采取18F-FDG PET-CT显像检查有无肿瘤复发现象；第二组20例，临床上已经被怀疑存在肿瘤复发情况，利用18F-FDG PET-CT显像技术进行明确诊断。探讨18F-FDG PET-CT显像在妇科肿瘤复发中的临床应用价值。结果：第一组中有8例患者在治疗后首次进行18F-FDG PET-CT显像检查结果呈阴性，其中1例患者在半年后再次进行18F-FDG PET-CT显像呈阳性，经过检查以及手术证实为消化系统癌症；另外2例患者18F-FDG PET-CT显像结果虽然为阳性，但是经过检查并未发现有肿瘤复发的现象，且至今身体状况良好，所以考虑术后改变导致的18F-FDG PET-CT结果呈现假阳性。第二组中15例患者的18F-FDG PET-CT显像结果呈阳性，其中3例经过手术病理证实为肿瘤复发；而另外12例给予化疗或放疗措施，其中7例患者的肿瘤病灶缩小，2例患者因为治疗无效而死亡，3例患者的病灶并无明显的变化；5例患者的18F-FDG PET-CT显像结果为阴性，其中2例再次进行18F-FDG PET-CT检查时结果为阳性，经手术证实为肿瘤复发，另外3例患者至今没有发现复发现象。结论：18F-FDG PET-CT显像对妇科恶性肿瘤的复发可以及时诊断出来，从而可以对复发患者进行及时而针对性的治疗，降低患者的痛苦以及死亡率，18F-FDG PET-CT显像是一种有效的方法，对于在临床治疗肿瘤方面制定和调整方案有着重要的意义。%Objective: To evaluate application value of18F-FDG PET-CT in diagnosing recurrent gynecologic carcinoma.Method: We chose 30 patients with gynecologic carcinoma after diagnosing and divided these patients into two groups. The first group contained 10 cases, they underwent the18F-FDG PET-CT to examine the recurrent carcinoma after treatment. The second group contained 20 cases, and they were suspicious of recurrence in the clinic and they underwent the18F-FDG PET-CT.Result: In the first group, there were 8 cases were negative results after undergoing the18F-FDG PET-CT, including 1 case was positive result when undergoing the second18F-FDG PET-CT examine, and proved to be digestive system cancer, 2 cases with positive result were diagnosed post-treatment changes. In the second group, 15 cases were positive results and 3 cases were proved to recurrent or move by operation, and the other 12 cases were given chemotherapy or radiotherapy, then 7 patients’ recurrent tumor volume reduced, and 2 cases died, 3 patients’ tumor had no change. The other 5 cases were negative results, but 2 cases changed to be positive results after the second examination and proved to be recurrent carcinoma.Conclusion: The18F-FDG PET-CT examination is helpful to diagnose and treat the recurrent carcinoma earlier. It can reduce the pain of the patients and mortality, it is an effective method of monitoring of gynecologic carcinoma recurrence, and has important clinical significance to formulate and adjust the treatment plan in the clinic.