Case report of the fourth laparoscopic liver resection and review of repeat laparoscopic resection for recurrent hepatocellular carcinoma in cirrhotic liver

摘要

A 73-year-old woman with liver cirrhosis caused by hepatitis C virus(HCV)underwent treatment of three hepatocellular carcinomas(HCCs)in liver segment 4,following three previous laparoscopic liver resections(LLRs)over 73 months.Contrast-enhanced computed tomography showed three 0.5-1.2 cm HCCs deep within the portal territories of subsegments 4a and 4b.The patient underwent laparoscopic resection of 4a and 4b,with the preservation of the portal branch to 4c,after minimal adhesiolysis around segment 4.The operation lasted 284 min,there was 50 mL of intra-operative bleeding and her recovery was uneventful.She was well,had experienced no recurrence and was HCV-negative,after taking oral anti-HCV therapy,21 months later.LLR is associated with fewer adhesions after surgery and requires less adhesiolysis,because the laparoscope and forceps can be used in the small spaces between adhesions.The present patient underwent four LLRs over 6 years without severe deterioration of liver functional reserve.LLR is a useful localized therapy,which can be performed repeatedly and may prolong the survival of patients with multicentric metachronous HCCs.