首页> 中文期刊>岭南现代临床外科 >血浆白蛋白水平在烧伤患者中预测死亡率的研究

血浆白蛋白水平在烧伤患者中预测死亡率的研究

     

摘要

目的研究烧伤患者的血浆白蛋白水平是否能够预测死亡率。方法选取大于16岁烧伤患者,收集其临床资料,包括如简明烧伤严重指数(ABSI),血浆白蛋白,球蛋白,血脂等。ROC曲线下面积用来评估白蛋白对死亡率的预测。结果486人纳入本研究,83.1%患者的烧伤面积小于30%,16.9%的患者烧伤大于30%。最为常见的烧伤原因是火焰。患者工作情况,烧伤性质,全层烧伤,吸入性烧伤,血白蛋白在存活患者与死亡患者中的分布显著不同(P<0.05)。存活患者与死亡患者相比,烧伤面积,入院ABSI,总胆固醇,甘油三酯,球蛋白,白蛋白,总蛋白值有显著地差异(P<0.05)。白蛋白,总蛋白,白球蛋白比,球蛋白,总胆固醇,甘油三酯预测死亡率的ROC曲线下面积分别是0.861,0.852,0.836,0.756,0.744,0.372。结论入院时,白蛋白水平在烧伤患者中可以当做敏感性及特异性标记物来预测死亡率。%Objective To investigate whether the level of serum albumin to predict mortality in burn patients. Methods The clinical data in burn patients aged more than 16 years old were analyzed,including abbreviation of burn severity index(ABSI), plasma albumin, globulin, blood fat. The ROC curve was used to evaluate albumin level on mortality prediction...Results 486 people were included in this study,.and most of them with burn area were less than 30%. (83.1%),.only 16.9% of patients were more than 30%..The most common cause was a flame injury..Work situation,.burn properties, full-thickness burns, inhalation burn, blood albumin in the distribution of live and death in patients were significantly different (P<0.05). There was a significantly difference between survival patients and death patients, in burn area,.hospital ABSI, total cholesterol, triglycerides, globulin, albumin, total protein (P<0.05). The areas under ROC curve for mortality prediction on the levels of albumin, total protein,.white globulin ratio,.globulin,.total cholesterol,.triglyceride predicts mortality of area under the ROC curv e respectively were 0.861,0.852,0.836, 0.756, 0.744, 0.372. Conclusion On admission,.albumin levels in patients with burns can be as a sensitive and specific marker to predict mortality.

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