首页> 中文期刊> 《检验医学与临床》 >硫酸钙/骨基质明胶在修复兔尺骨骨缺损中的实验研究

硫酸钙/骨基质明胶在修复兔尺骨骨缺损中的实验研究

         

摘要

目的:探讨硫酸钙/骨基质明胶可降解复合人工材料用于兔尺骨骨缺损的修复效果。方法选取已建立尺骨缺损模型家兔30只,采用随机数字表法将其分为3组,即空白对照组、单纯硫酸钙组及硫酸钙/骨基质明胶组,比较3组家兔术后12周骨痂形成率、骨性修复率及双轨征出现率、骨缺损修复 X 线片评分、尺骨扭转强度等。结果硫酸钙/骨基质明胶组骨痂形成率为93.33%、骨性修复率为86.67%、双轨征出现率为93.33%、骨缺损修复X 线片评分(11.85±2.14)分、尺桡骨扭转强度(0.87±0.13)N × M ,5项均明显高于单纯硫酸钙组和空白对照组,差异有统计学意义(P<0.05)。结论硫酸钙/骨基质明胶可降解复合人工材料,用于兔尺骨骨缺损修复效果显著,可有效促进骨痂形成及骨结构修复。%Objective To explore the reparative effect of CS /BMG biodegradable artificial material on the de-fect of rabbit ulna bone .Methods Thirty rabbits on which ulna defect model had been established were selected ,di-vided into three groups that normal control group ,pure CS treatment group and CS /BMG group by using the random number table method ,then compared these datas that bone callus formation rate ,bony rate ,rate of dual track ap-peared ,bone defect repair X-ray score ,ulna torsional stresses among three groups in the following 12 weeks .Results CS/BMG group bony callus formation rate ,estoration rate ,the double-track sign rate ,bone defect repair X-ray score , ulna torsional stresses were 93 .3% ,86 .7% ,93 .3% ,(11 .85 ± 2 .14) ,(0 .87 ± 0 .13)N × M ,which were higher than the pure CS group and blank control group (P< 0 .05) .Conclusion The reparative effect of CS /BMG biodegradable artificial material on the defect of rabbit ulna bone is remarkable .

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