目的探讨女性乳腺良性病变和乳腺癌患者外周血中D‐二聚体水平的变化及其临床意义。方法收集乳腺外科住院患者164例，其中88例良性病变患者和76例乳腺癌患者（无淋巴结转移者35例，有淋巴结转移者41例）。采用Sysmex CA7000全自动凝血仪检测患者血浆D‐二聚体水平。结果乳腺癌患者和乳腺良性病变的D‐二聚体水平分别为0．28（0．18～0．45）、0．26（0．17～0．42）mg／L ，差异无统计学意义（P＞0．05）。有淋巴结转移和无淋巴结转移的乳腺癌患者D‐二聚体水平分别为0．29（0．22～0．40）、0．24（0．15～0．50）mg／L ，差异也无统计学意义（P＞0．05）。结论 D‐二聚体水平与乳腺癌及有无淋巴结转移无密切相关性。%Objective To explore the changes of D‐dimer levels in breast benign lesions and breast cancer fe‐males and its clinical significance .Methods 164 cases of hospitalized patients in Department of Breast Surgery were selected ,of which there were 88 cases of breast benign lesions patients and 76 cases of breast cancer (35 cases with‐out lymph node metastasis ,41 cases with lymph node metastasis) .Plasma D‐dimer level detection was performed on Sysmex CA7000 automatic blood coagulation analyzer .Results The D‐dimer levels of breast cancer patients and pa‐tients with breast benign lesions were 0 .28(0 .18-0 .45) and 0 .26(0 .17-0 .42)mg/L respectively ,and there was no significant difference (P>0 .05) .The D‐dimer levels of breast cancer patients with lymph node metastasis and with‐out lymph node metastasis were 0 .29(0 .22-0 .40) and 0 .24(0 .15-0 .50)mg/L respectively ,and there was no sig‐nificant difference (P>0 .05) .Conclusion D‐dimer level correlates with neither breast cancer nor lymph node metas‐tasis .
展开▼
