酪酸菌对小鼠有害气体排放的影响

摘要

目的 探讨酪酸菌对小鼠有害气体排放的影响.方法 80只KM小鼠分4组,每组20只,雌雄各半,Ⅰ组为对照组,Ⅱ组、Ⅲ组、Ⅳ组分别连续21 d灌胃酪酸菌500 mg/kg、1 000 mg/kg、1 500 mg/kg,每日测定独立通气笼内氨(NH3)和硫化氢(H2S)浓度,试验21d测定各组小鼠生长性能、小鼠粪便中脲酶活性.结果 与对照组相比,Ⅲ组、Ⅳ组小鼠的平均日增重略有提高,但没有统计学差异;灌胃后7d,Ⅲ组、Ⅳ组笼内NH3含量明显低于Ⅰ组和Ⅱ组(P＜0.05),各组均未检测到H2S.结论 酪酸菌可能会影响小鼠的生长性能和氨的排放.%Objective To explore the influence of butyric acid bacteria on harmful gas emissions in KM mice.Methods Eighty KM mice were randomly divided into four groups (group Ⅰ,Ⅱ,Ⅲ and Ⅳ) with equal number of females and males in each group.The mice in group Ⅱ,Ⅲ and Ⅳ were fed with butyric acid bacteria at the dose of 500 mg/kg、1000 mg/kg、1500 mg/kg by gavage for 21 d,respectively,and group Ⅱ as control.The concentration of ammonia and hydrogen sulfide were monitored every day,and the growth performance,the activity of urease in faeces in each group were tested at 21 d.Result Compared to the control group,the average daily weight gain of group Ⅲ and group Ⅳ were improved.On day 7 of gavage,the ammonia emission of group Ⅲ and Ⅳ were significantly lower than that of group Ⅱ and group Ⅱ (P＜0.05),while the H2S emission were not edfected.The urease activities of group Ⅲ and Ⅳ were lower than group Ⅰ and Ⅱ,but not significantly (P＞0.05).Conclusion The butyric acid bacteria may improve the production performance and reduce the ammonia emission of mice.