Objective To obtain anatomical data of radius in New Zealand white rabbits with different age by three-dimensional reconstruction technique of CT images and provide references for rabbit bone defect experiment and bone tissue engineering scaffold manufacture.Methods Forty male New Zealand white rabbits aged 3 months and 6 months were included respectively in this study.According to their age,the rabbits were divided into group A (3 month) and group B (6 month).Computed tomography (CT) scanning of bilateral radius was conducted and the contours of 3D-reconstructed radius were observed by Mimics 10.0,the anatomical parameters including the length of radius,transverse diameters and sagittal diameters of middle of radius,front curvature angleandlateral curvature angle were measured respectively.Results The contours of radius were bulky at ends,narrow in the middle.The obvious camber was observed in radial middle,and the mean front curvature were (24.19 ± 1.18)° in group A and (23.97 ± 1.35) ° in group B,and the lateral curvature angles were (26.13 ± 1.04)° in group A and (25.66 ± 1.23)° in group B respectively,and there was no significant difference between the two groups (P＞0.05).The straight and curvilinear length of radius were (63.05 ± 1.33) mm and (65.03 ± 1.10) mm in group A,and (66.56 ± 1.53) mm and (70.41 ± 1.06) mm in group B respectively,with no significant difference (P＜0.05).The transverse diameters of the middle of radius were (4.24 ± 0.19) mm in group A and (4.30 ± 0.23) mm in group B.The sagittal diameters of the middle of radius were (3.23 ± 0.16) mm in group A and (3.29 ± 0.18) mm in group B respectively.There was no significant difference between the two groups with regard to sagittal diameters (P＞0.05).And the transverse diameters and the sagittal diameters of the middle of radius were not correlated with length of radius (P＞0.05).Conclusions It is feasible to accurately identify the contours and bony landmarks on the three-dimensional reconstruction of the radius.Digital measurement can provide accurate parameters for establishment of bone defect model and manufacture of bone-tissue engineering scaffold.%目的 利用CT图像三维重建技术获取不同月龄新西兰兔桡骨的解剖学数据,为兔骨缺损实验研究及制造骨组织工程支架提供参考.方法 选取3月龄及6月龄雄性新西兰白兔各20只,根据兔月龄不同分为A组(3月龄)及B组(6月龄),所有兔双侧桡骨行CT扫描,应用Mimics10.0软件行数字化三维重建技术重建桡骨,标定桡骨解剖标志后测量桡骨长度,桡骨中点矢状径、横径,前曲角及侧曲角.结果 新西兰白兔桡骨两端粗大、中间细小,中段存在明显弧形凸起,A组及B组前曲角分别为(24.19±1.18)°及(23.97±1.35)°,侧曲角分别为(26.13±1.04)°及(25.66±1.23)°,二者差异均无统计学意义(P＞0.05);A组桡骨线性长及曲线长分别为(63.05±1.33)mm及(65.03±1.10) mm,B组分别为(66.56±1.53) mm及(70.41±1.06)mm,组间比较差异均具有统计学意义(P＜0.05).A组、B组桡骨中点横径分别为(4.24±0.19)mm及(4.30±0.23)mm;中点矢状径分别为(3.23±0.16 mm)及(3.29±0.18) mm.中点横径、矢状径与桡骨长度均无相关性(P＞0.05).结论 基于CT影像的新西兰白兔桡骨数字化三维重建技术能良好反映桡骨外形,可清晰识别桡骨解剖标志并进行解剖学测量,为兔骨缺损实验研究及组织工程支架制造提供解剖数据.
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