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西洋参提取物增强免疫力作用的实验研究

     

摘要

[Objective] To study the effects of American Jingsen on regulating and boosting immunity. [Methods] Using the enhancing immune function methods of "health food functional evaluation procedures and inspection method", we studied Con A- induced lymphocyte prolife ration, the serum hemolysin formation, antibody-producing cells in mice and phagocytosing function of peritoneal macrophage. [Result] In comparison with the blank control group, American Jingsen was found to have increases of ConA- induced lymphocyte prolife ration, as well as phagocytosing function of peritoneal macrophage and hemolysin antibody concentration. [Conclusion] It showed that American Jingsen could enhance immune function.%[目的]验证西洋参提取物的增强免疫力作用.[方法]以小鼠为实验对象,研究西洋参提取物对刀豆蛋白A(concanavalin,ConA)诱导的小鼠脾淋巴细胞转化试验、小鼠血清溶血素测定、抗体生成细胞检测(Jerne改良玻片法)、小鼠腹腔巨噬细胞吞噬鸡红细胞试验、脏器/体重比值等试验的影响.[结果]与阴性对照组比较,西洋参提取物能提高ConA诱导的小鼠脾淋巴细胞增殖能力、提高小鼠血清溶血素抗体积数水平、增加小鼠溶血空斑数、提高小鼠腹腔巨噬细胞吞噬鸡红细胞的吞噬率;差异均有显著性(P<0.05).[结论]西洋参提取物具有增强免疫力作用.

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