电针治疗严重功能性便秘有效性和安全性随机对照试验研究

摘要

Objective] Through randomized controlled clinical study, evaluate the effectiveness of electro-acupuncture in the treatment of severe functional constipation.[Method]70 cases of patients with SFC were randomly divided into electro-acupuncture group(35 cases) and sham electro-acupuncture group (35 cases). EA group was treated with electro-acupuncture deep needling at targeted acupoints, while Sham EA group with Sham EA shallow needling on next-acupoints. We compared effectiveness between and within two groups after 8 weeks' treatment and 12 weeks' follow-up.[Results] The difference of frequence of CSBM and SBM between and within two groups showed significant differences(P<0.05). In follow-up period, the differences of frequence of CSBM every 4 weeks between and within two groups were statistically significant(P<0.05), [Conclusions] Electro-acupuncture deep needling has a better and more steady effect on SFC.%[目的]通过随机对照临床研究，评价电针治疗严重功能性便秘的有效性。[方法]将70例严重功能性便秘患者随机分为电针组(35例)和假电针组(35例)。电针组采用电针深刺穴位的疗法，假电针组采用假电针浅刺非经非穴的疗法，治疗8周及随访12周后比较疗效。[结果]在增加完全自主排便次数方面，电针组从第4周开始优于治疗前（P＜0.05），而假电针组从第8周开始优于治疗前（P＜0.05）；电针组与假电针组治疗4、8周后比较，差异均有统计学意义（P＜0.05）；治疗第4、8周及随访第12周，电针组均优于假电针组(P<0.05）。在增加自主排便次数方面，两组从第4周开始优于治疗前（P＜0.05）；电针组治疗4、8周后比较，差异有统计学意义（P＜0.05）；治疗第4、8周及随访第12周，电针组均优于假电针组(P＜0.05)。[结论]电针深刺经穴治疗严重功能性便秘有近期与远期疗效，起效快，且疗效稳定。