急性心肌梗死后心率变异性和心源性猝死危险性的关系

摘要

AIM:To study the correlation of of heart rate varia-bility (HRV)and risk of sudden cardiac death (SCD)after acute myocardial infarction (AMI).METHODS:35 cases of patients with SCD after AMI received in our hospital were selected and other 35 healthy persons were chosen as research object retrospec-tively from June 2010 to June 2014,differences of related indexes of clinical HRV were observed and compared between the two groups.HRV parameters in patients with SCD after AMI were ex-plored,to provide the reference to clinical prognosis. RE-SULTS: Compared with healthy people, the HRV indexes SDNN,SDANN,RMSSD,PNN50 and LF /HF in patients with sudden death after AMI were significantly lower (P <0.05 ). CONCLUSION:There are obvious differences in HRV indexes between patients with SCD after AMand healthy people.And the occurrence risk of SCD can be predicted based on the characteris-tics of HRV data in clinical diagnosis,which can reduce the oc-currence rate of SCD in the clinical prognosis and strengthen prog-nosis after AMI.%目的：探讨急性心肌梗死（AMI）的心率变异性（HRV）与心源猝死（SCD）风险的相关性．方法：选择2010-06／2014-06间我院接收的35例 AMI 后 SCD 患者和同期体检健康者35例作回顾性研究，对比观察两组人群的临床 HRV相关指标数据的差异．探讨临床 AMI 后的 SCD 患者的 HRV各指标特征，为临床预后提供参考依据．结果：同健康者相比，发生 AMI 后猝死患者的全窦性心搏 RR 间期标差（SDNN）、RR 间期平均标差（SDANN）、RR 间期邻差方根（RMSSD）、50 ms 以上 NN 期邻差百分比（PNN50）与低高频比值（LF ／HF）等 HRV 指标数据值均显著更低（P ＜0．05）．结论：AMI 后发生 SCD 者的 HRV 各项指标数据与健康者间存在明显差别，在临床诊断中可根据受检者的 HRV 数据特征对其发生 SCD 的风险进行预测，可起到降低临床中 SCD 发生率及加强 AMI 预后的作用．