AIM: To observe the curative effect of external ap⁃plication of Ruyijinhuang powder combined with vinegar in pre⁃vention of phlebitis caused by chemotherapy drugs. METHODS:A total of 80 tumor patients with peripheral venous chemotherapy admitted into Oncology Department of Integrated Traditional Chi⁃nese and Western Medicine, Affiliated Hosoital of Hebei Univer⁃sity from December 2012 to December 2013 were randomly divid⁃ed into experimental group ( n=40 ) and control group ( n=40 ) . After infusion of chemotherapeutic drugs, the experimental group was treated by external application of Ruyijinhuang powder com⁃bined with vinegar for 5 consecutive days, and changed once dai⁃ly. The local skin and blood vessels were observed dynamically. The control group only received dynamic observation on local skin and blood vessels. At the same time, the occurrence of phlebitis of two groups should be observed closely. RESULTS:The incidence of phlebitis in the experimental group was 12.5%, which was lower than 35.0%of the control group, and the difference was statistically significant(P<0.05). CONCLUSION: It�s effective to use exter⁃nal application of Ruyijinhuang powder combined with vinegar in prevention of phlebitis caused by chemotherapy drugs, with easier operation and fewer side effect. It�s worthy of clinical promotion.%目的：观察醋调如意金黄散局部外敷预防化疗药物引起的静脉炎的疗效．方法：选取2012－12／2013－12在河北大学附属医院中西医结合肿瘤科行外周静脉化疗的80例肿瘤患者，随机分为试验组（ n＝40）与对照组（ n＝40）．试验组在输注化疗药物结束后局部外敷醋调如意金黄散，连用5 d，每天更换一次，并对患者局部皮肤及血管情况进行动态观察．对照组不采用如意金黄散局部外敷，每天仅对患者局部皮肤及血管情况进行动态观察．密切观察两组静脉炎的发生情况．结果：试验组静脉炎的发生率为12．5％，对照组静脉炎的发生率为35．0％，且试验组静脉炎的发生程度均较轻．试验组静脉炎的发生率低于对照组，差异具有统计学意义（P＜0．05）．结论：应用醋调如意金黄散局部外敷能有效地预防化疗药物引起的静脉炎的发生，且操作简单，副作用小，值得临床推广．
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