6–叠氮基取代半乳糖苷的合成

摘要

6–叠氮基取代半乳糖苷是糖化学合成中的重要中间体,广泛应用于各种功能性寡糖单元的构建.本研究以半乳糖为原料,探讨高效简洁的6–叠氮基取代半乳糖苷的合成方法,为后续合成具有流感病毒抑制作用的唾液酸–半乳糖及其多价蛋白缀合物提供实验基础.%6-azido galactose is an important intermediate in carbohydrate chemistry,and widely used in the construction of building blocks of various functional oligosaccharides.In this research,an efficient and concise method for synthesising 6-azido galactoside using galactose as the starting material was used,which provides an experimental basis for further syn-thesing sialogalactosides and their protein conjugates as anti-influenza glycocomplexes.