普洱茶茶褐素对大鼠肠道菌群的影响

摘要

本研究以普洱茶茶褐素（分子量＞50 kDa，TB）为研究对象，通过灌胃茶褐素后分析大鼠体内微生物变化，揭示普洱茶茶褐素对肠道菌群的影响。结果显示，茶褐素能显著改善抗生素的脱污染作用，调整肠道菌群失调，且具有促进大鼠肠道乳酸杆菌、双歧杆菌增殖，抑制大肠杆菌、肠球菌生长的作用，并随时间延长，效果愈加明显；而微生物的大量繁殖可加速茶褐素的分解代谢。%In this study, theabrownin (Mw>50 kDa, TB) extracted from pu-erh tea was used as experimental material, and the effects of theabrownin to the intestinal flora of rat was studied. The results showed that the theabrownin had remarkable effects on the intestinal flora in rats. TB could significantly improve the de-pollution of antibiotics and adjust the intestinal flora imbalance. It was found that TB could promote the proliferation of Bifidobacterium and Lactobacillus and inhibit the proliferation of Escherichia coli and Enterococcus. The effects are more obvious with increasing culture time. In turn, microbes proliferate can accelerate the catabolism of theabrowns.