Knowing Man's innate clocks functioning allows to understand WHEN and WHY therapies are efficient.Vigil chronotypes determination and respect allows to avoid scholars' failure.Performances depend on chronotypes and time changes.Both minimal and maximal durations of night sleep cycles result from interactions between endogenous and exogenous clocks.Our ecoexotope is structured by solar,lunar and terrestrial rhythms which are synchronisers for endophysiotope clocks.Man night sleep changes depend on lunar cycles entrainment.Sleep analyses point to circa-annual solar rhythms used as controls to evidence circa-monthly lunar ones.To evidence physiological responses individual longitudinal records are used.To evidence lithotherapeutic effects,stimuli responses are tested according to a double-blind placebo-controlled survey.WHAT mineral to chose?,WHY?,HOW to treat?,WHEN? Compared with controls,jadeite or nephrite enhances night sleep quality with a 15 fold decrease of awakenings and urinations.The highest placebo effect was below 4 fold increase.Depending on minerals and trace elements,properties change.The mineral crystal structure is evidenced to have an action.The contact area with the skin is a limiting factor.Placebo effects are greater during the day phase.Red jasper treatment enhances the number and intensity of diurnal physical working.Minerals act in a dose-dependent manner and in synergy.Hematite sole gives a placebo effect,but increases the effect of serpentinite by a 15 fold value.Within a clocks network,the latency phase of the whole is shorter than the shortest latency phase of each clock,enhancing the system reactivity.
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