Objective:To investigate the effect of excessive additive iodine intake on reproductive organs of male weanling rats. Methods:One hundred and three male weanling rats were fed with feedstuff containing 0,0.5.1.2.5,and 5- fold higher dosage of iodine in standard iodine-additive salt,i.e.200,300,400,700,and 1200μg/kg,respectively, for 130-136 days.The number of rats taking different dosages of iodine was 20,21,21,21,20 respectively.The rats fed 200μg/kg of iodine were taken as the control group.For all groups,their structural changes of reproductive organs and sperm quality were evaluated. Results:The three experiment groups fed with 1,2.5,and 5-fold higher dosage iodine showed apparent reduction in testicular weight(P<0.05-0.01) by 10.76%,14.58%and 25.35%,respectively,compared with the control. But significant reduction in testis/body weight ratio was only observed in the 5-fold higher dosage group.The sperm concentration and total sperm count declined in four experiment groups fed with 0.5-5 fold higher dosage of iodine.The sperm concentration was reduced by 6.59%,22.53%,17.35%and 18.06%respectively.The percentage of sperm with normal and abnormal form significantly changed(P<0.05).The addition of different doses of iodine showed no apparent adverse effects on other reproductive organs or sperm viability. Conclution:These results indicated that excessive iodine intake might cause potential hazards on reproductive organs of male rats with respect to spermatogenesis.
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机译:“汽车超限自动检测系统”研制(The Produce and Research of Automatic Monitoring System in The Condition of The Loadin Excessive Limitation About The Transport of Automobile)