卵巢恶性甲状腺肿的诊断及治疗并1例病例分析

摘要

目的 探讨卵巢恶性甲状腺肿的诊断及治疗. 方法 汇报1例北京协和医院妇产科诊治的恶性甲状腺肿病例,并进行文献复习及总结. 结果 卵巢恶性甲状腺肿为少见的卵巢恶性生殖细胞肿瘤,发病率低,文献多为单个病例报告或小型病例系列研究.目前认为手术为首选治疗方法,早期患者可行保留生育的手术,但若术中肿瘤破裂,应行完整分期手术,晚期患者应行分期手术,术后均应辅助甲状腺切除、131I治疗及甲状腺素治疗. 结论 卵巢恶性甲状腺肿发病率低,治疗方法首选手术治疗,手术范围应取决于患者的生育要求、肿瘤情况及分期,并术后辅助治疗.%Objective:To investigate the diagnosis and treatment of malignant struma ovarii (MSO).Methods:A patient of MSO in PUMC hospital was reported and the related literatures were reviewed.Results:MSO is a rare malignant ovarian germ cell tumor with low morbidity.The published literatures are mostly single case or small case series.Surgery is thought the optimal management.The early stage patients can be performed fertility-sparing surgery,but if the tumor breaks during surgery,complete staging surgery should be done.However,advanced patients should be performed staging surgery directly.After that,all patients should receive total thyroidectomy,radioactive iodine-131 ablation and thyroxine treatment.Conclusions:The incidence of MSO is low,and the preferred treatment is surgery.The surgical range depends on the fertility-sparing desire of patients and the tumor status and staging,and adjuvant radioactive iodine-131 ablation after surgery is also necessary.