首页> 中文期刊> 《齐齐哈尔医学院学报》 >复方樟柳碱联合地塞米松离子导入治疗眼外肌麻痹的疗效观察

复方樟柳碱联合地塞米松离子导入治疗眼外肌麻痹的疗效观察

         

摘要

Objective To review the effect of compound anisodine hydrobromide combined with dexamethasone iontophoresis in treatment of extraocular palsy.Methods 36 cases of extraocular palsy patient were divided into 2 groups in random.Control group used danhong injection 20ml qd, 10d a course of treatment. Continuous treatment 2 ~4 course according to patient's condition.Therapy group to plus arterial temporalis superficialis side hypodermic injection in trouble eye with 2ml compound anisodine hydrobromide combine dexamethasone iontophoresis, qd, 10 days a course.Continuous treatment 2 ~4 course according to patient's condition.To observe the diplopic get better status, position of eye and recover of eye movement status.Results In therapy group, cured 16 cases (88.9%), improved 1 case, inefficacy 1 case, total effective rate was 90%.In Control group, cured 11 cases (60%), improved 3 case, inefficacy 4 case, total effective rate was 77%.The cure rate was significant differenct between 2 groups(P <0.05).Conclusions Treatment with compound anisodine hydrobromide combined with dexamethasone iontophoresis can obviously improve the effect for extraocular palsy, has no adverse reaction or complication.%目的:观察复方樟柳碱联合地塞米松离子导入治疗眼外肌麻痹的临床疗效。方法将36例(36眼)眼外肌麻痹患者随机分为治疗组及对照组,每组各18例(18眼)。对照组全身应用活血化淤治疗,静滴丹红注射液20 ml qd,10 d为1个疗程,根据病情连续治疗2~4个疗程,治疗组加用复方樟柳碱2 ml行颞浅动脉旁注射联合地塞米松离子导入,每天1次,10 d为1个疗程,根据病情连续治疗2~4个疗程;观察两组病例复视好转情况、眼位及眼球运动恢复情况。结果治疗组18例中治愈16例(88.9%),好转1例,无效1例,总有效率90%,对照组18例中治愈11例(60%),好转3例,4例无效,总有效率77%。两组治愈率有显著性差异(P<0.05)。结论复方樟柳碱联合地塞米松离子导入治疗眼外肌麻痹能明显提高疗效,无副作用及并发症。

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