Objective To explore the acute non-metallic titanium clip and intravenous injection hemostasis efficacy and safety in patients with gastrointestinal bleeding endoscopic assisted .Methods A retrospective analysis of 82 patients in our hospital from January 2015-March 2016 admitted on acute non-vein upper gastrointestinal bleeding , according to the different treatment regimens divided into two groups , the endoscopic hemostatic drug injection treatment of 35 patients as a control group , 47 patients endoscopic assisted by metal clip hemostatic treatment observation group , and then the two groups were compared and safety conditions assisted .Results The bleeding rates of observation group was higher than the control group after treatment 0.5 days, one day, two days, and 72h rebleeding, surgical proportion of 2.13%, 2.13%compared with the control group, 22.86%, 20.00%lower, and effectively stop bleeding, stop bleeding instantly proportion of 97.87%, 97.87%compared with the control group , 77.14%, 80.00%higher, after which a significant difference in 2d, and the difference was statistically significant (P<0.05);and 72h rebleeding, surgery low share ratio than the control group , effective hemostasis , immediate hemostasis high proportion than the control group , the difference was statistically significant (P<0.05);the observation group vomiting disappeared time (2.58±0.45) d, fecal occult blood transfer Yin time (4.20±0.28)d than the control group (4.35±1.20)d, (7.80±0.85) d shorter ( P<0.05) , and the comparison of the two groups overall complication rate had no significant difference , which was not statistically significant ( P>0.05) .Conclusions The study shows that acute upper gastrointestinal bleeding in patients with non-vein assisted endoscopic hemostatic titanium clips treatment effect is remarkable .It can improvehemostasis rate of different time periods , promote clinical symptoms and safety , which has a great clinical application value .%目的：探究急性非静脉上消化道出血患者行内镜辅助下金属钛夹和注射止血治疗的效果及安全性。方法选择本院2015年1月至2016年3月收治的急性非静脉上消化道出血82例患者予以回顾性分析，按照治疗时所用不同治疗方案分成两组，将行内镜辅助下止血药物注射医治35例患者作为对照组，将行内镜辅助下金属钛夹止血医治47例患者设为观察组，对两组疗效和安全性情况进行对比。结果观察组治疗后0．5d、1d、2d止血率均比对照组高，其中2d的止血率差异显著，观察组72h再出血、外科手术所占比例2．13％、2．13％均较对照组22．86％、20．00％低，其有效止血、即时止血所占比例97．87％、978．7％均较对照组77．14％、80．00％高；差异具有统计学意义（P＜0．05）；观察组呕血消失时间（2．58±0．45） d、大便潜血转阴时间（4．20±0．28）d均比对照组（4．35±1．20）d、（7．80±0．85）d短（P＜0．05），两组并发症发生率对比无明显差异（ P＞0．05）。结论急性非静脉上消化道出血患者行内镜辅助下金属钛夹止血医治效果显著，能够提高不同时间段止血率，促进患者临床症状改善，且安全性高，具有临床推广及应用价值。
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