Ionic liquids functionalized β-cyclodextrin polymer,a mono-6-deoxy-6-(1.2-dimethylimidazolium)-(5-cyclodextrin iodide polymer(ILs-β-CDCP).was synthesized as a solid-phase adsorbent coupled with high-performance liquid chromatography for separating or analyzing magnolol in drug samples.The results showed that magnolol was adsorbed rapidly on ILs-β-CDCP and eluted with methanol.Under the optimum conditions,preconcemration factor of the proposed method was 12.The linear range,limit of detection(LOD).correlation coefficient(R) and relative standard deviation(RSD) were found to be 0.02-8.00 μg/mL,1.9 ng/mL,0.9992 and 2.76%(n=3,c=2.00 μg/mL),respectively.The interaction between ILs-β-CDCP and magnolol was studied through the inclusion constant,FTIR and TGA analysis.This proposed method has been successfully applied to the determination of magnolol in real samples.
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