C反应蛋白对老年髋部骨折患者术后1年死亡率及并发症的影响

摘要

目的:探析C反应蛋白(CRP)水平对老年髋部骨折患者术后1年死亡率及并发症的影响.方法:分析846例老年髋部骨折患者的临床资料,比较术后死亡组与生存组,并发症组与无并发症组的CRP水平.多因素Logistic回归分析CRP水平与老年髋部骨折患者术后1年死亡率及并发症发生率的关系.结果:死亡组患者的CRP水平明显高于生存组,且CRP<8 mg/L患者的死亡率明显低于8 mg/L≤CRP<40 mg/L患者与CRP≥40 mg/L患者(P<0.05).并发症组与无并发症组的CRP水平比较差异无统计学意义,且CRP<8 mg/L患者、8 mg/L≤CRP<40 mg/L患者与CRP≥40 mg/L患者的并发症发生率均无明显统计学差异(P>0.05).CRP水平与老年髋部骨折患者术后1年死亡率存在显著正相关性(P<0.01),但与术后1年并发症发生率无明显相关性(P>0.05).结论:检测术前CRP水平可有效预测老年髋部骨折患者术后1年死亡率情况, CRP水平越高,死亡率则越高.%Objective:To analyze the effect of CRP on postoperative 1-year mortality and complications in gerontal patients with hip fractures.Methods:Clinical data of 846 gerontal patients with hip fracture were retrospectively analyzed.The levels of CRP in death group and survival group,the levels of CRP in complication group and non-complication group were compared.Multivariate logistic re-gression analysis was used to analyze the relationship between CRP level and postoperative 1-year mortality and complication rate in ge-rontal patients with hip fractures.Results:The CRP levels in death group were obviously higher than that in survival group,and the death rate in the patients with CRP<8mg/L was obviously lower than that in the patients with 8mg/L≤CRP<40mg/L and CRP≥40mg/L (P<0.05).The CRP levels in the complication group and non-complication group had no statistical difference,and the death rates in the patients with CRP<8mg/L,8mg/L≤CRP<40mg/L and CRP≥40mg/L had no statistical difference (P>0.05).There was a significant positive correlation between CRP levels and 1-year postoperative mortality in gerontal hip fractures (P<0.01),but there was no significant correlation with the incidence of complications after 1 year(P>0.05).Conclusion:The levels of CRP before the operation can effectively predict the 1-year postoperative mortality in the gerontal patients with fracture of hip.The higher the CRP levels,the higher the mortality rate.