目的 探讨声触诊组织定量(virtual touch quantification,VTQ)技术对甲状腺弥漫性病变的诊断价值.方法 应用VTQ技术对20例正常甲状腺者(正常对照组)和85例甲状腺弥漫性病变患者(病例组)进行检测,同时采用VTQ分析软件计算组织弹性顺应力的横向剪切波速度,分析甲状腺弥漫性病变的VTQ相关数据.结果 正常对照组(正常甲状腺)横向剪切波速度值为(1.54±0.42)m· s-1,病例组中的单纯性甲状腺肿横向剪切波速度值为(1.83±0.31)m·s-1,甲状腺功能亢进横向剪切波速度值为(1.96±0.53)m·s-1,亚急性甲状腺炎横向剪切波速度值为(2.34±0.24)m·s-1,甲状腺功能减低横向剪切波速度值为(3.34±0.12)m·s-1,桥本甲状腺炎横向剪切波速度值为(3.83±0.37)m·s-1.病例组中的单纯性甲状腺肿、甲状腺功能亢进、亚急性甲状腺炎、甲状腺功能减低、桥本甲状腺炎横向剪切波速度值与正常对照组比较差异均有统计学意义(均P＜0.05),单纯性甲状腺肿横向剪切波速度值与甲状腺功能亢进比较差异无统计学意义(P＞0.05),甲状腺功能减低、亚急性甲状腺炎、桥本甲状腺炎横向剪切波速度值与单纯性甲状腺肿、甲状腺功能亢进比较差异均有统计学意义(均P＜0.05),甲状腺功能减低、亚急性甲状腺炎横向剪切波速度值与桥本甲状腺炎比较差异均有统计学意义(P＜0.01).结论 VTQ技术在甲状腺弥漫性病变的诊断和鉴别诊断中具有较高的临床参考价值.%Objective To explore the diagnostic value of virtual touch quantization(VTQ) in diffuse thyroid disease. Methods The VTQ technique was used in 85 patients with diffuse thyroid disease (case group) and 20 normal subjects (control group). At the same time, transverse shear wave velocity was measured to calculate the elastic compliance using VTQ analysis software and the relevant data were analyzed for diffuse thyroid disease. Results Thetransverse shear wave velocity was (1.54 ± 0. 42)m ? S-1, (1. 83 ± 0. 31)m ? S-1 , (1. 96±0. 53)m ? S-1 , (2. 34 ± 0. 24)m ? S-1,(3. 34± 0. 12) m ? S-1 and (3. 83±0. 37)m ? S-1 in control, simple goiter, hyperthy-roidism,subacute thyroiditis, hypothyroidism and Hashimoto' s thyroiditis, respectively. Transverse shear wave velocity in control group was significantly greater than that in case group (all P<0. 05) ,but there were no obvious differences between simple goiter and hyperthyroidism (P> 0. 05). Transverse shear wave velocities in subacute thyroiditis,hypothyroidism and Hashimoto's thyroiditis were significantly greater than those in simple goiter and hyperthyroidism (all P<0. 05) ,and transverse shear wave velocities in hypothyroidism and subacute thyroiditis were obviously smaller than those in Hashimoto's thyroiditis (P展开▼
