目的 研究分析胃癌术后接受化疗后再次复发的影响因素. 方法 回顾性分析2009年3月~2011年4月,在笔者医院接受胃癌术后化疗后再复发的65例胃癌患者的临床、病理和生存资料,并采用Logistic多因素回归分析,对影响胃癌在接受化疗后复发的因素进行分析. 结果 在病理资料与复发时间的分析中,患者的性别(t=0.056,P=0.076)与年龄(t=0.320, P=0.063),不会直接影响患者的复发时间;而患者胃癌的分化程度(t=2.23,P=0.002)、切缘(t=5.36,P=0.032)、TMN分期(F=3.68,P=0.018),差异均有统计学意义;Logistic多因素回归分析显示患者的肿瘤直径(OR=3.56,P=0.001)、TNM分期(OR=6.48,P=0.006)以及Borrmann分型(OR=2.52,P=0.003)是胃癌化疗后再次复发的独立危险因素. 结论 胃癌在术后接受化疗后再次复发时间与患者性别、年龄无关,肿瘤直径、TNM分期、Borrmann分型是其再次复发的独立危险因素.%Objective To research the factors of gastric cancer recurrence in receiving chemotherapy .Methods A retrospective a-nalysis from 2009 March to 2013 April in our hospital were taken , 65 cases with gastric cancer were received chemotherapy treatment and survival data were analyzed , and the multi factor Logistic regression analysis were used , the influencing factors of the relapse after chemo-therapy in gastric cancer were analyzed .Results In the analysis of pathological data and time of recurrence:There were not significant difference the patient′s sex (t=0.056, P=0.076), age (t=0.320, P=0.063)with recurrent time, there were not directly affect pa-tients with recurrent time;and there were the difference among the patient′s degree of differentiation (t=2.230, P=0.002), the cutting edge (t=5.360, P=0.032), TMN staging (F=3.680, P=0.018) ; multivariate Logistic regression analysis showed that the size of the tumor patients (OR=3.560, P=0.001), TNM staging (OR=6.480, P=0.006) and Borrmann type (OR=2.520, P=0.003) were independent risk factors of relapse of gastric cancer after chemotherapy .Conclusion For gastric cancer patients during chemothera-py again, there are not difference among recurrence time , gender and age.Tumor size, TNM stage and Borrmann type are the independent risk factors of recurrence .
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