Objective By comparing the diagnostic efficacy of three kinds of diagnostic methods , we hoped to find the best method to improve the accuracy of diagnosis .Methods The 652 breast lesions from 523 women were undergoing conventional ul-trasound and real-time tissue elastography , diagnostic results were obtained with 5-score method in conjunction with conventional ultrasound.Then, we measured the lesion of the area ratio and strain ratio , the pathological results as the reference standard to construct test receiver operating characteristic curve ( ROC) , and the area under the curve and the optimal cut-off value of benign and malignant breast lesions diagnosis were got .Results The area under the curve and cutoff values of area ratio and strain ratio were 0.850, 1.43;0.907, 3.35 respectively.The sensitivity, specificity, accuracy of 5-score method, strain ratio method and area ratio method were 96.23%, 87.05%, 88.65%;92.31%, 74.58%, 85.59%;90.63%, 78.81%, 86.35%respectively. The 5-score method, area ratio method, strain ratio method diagnostic accuracy had no statistical difference ( P >0.05).Con-clusion 5-score method , area ratio method and strain ratio method had no significant difference in diagnostic accuracy , each method had respective advantages , it should be used flexible with the specific circumstances to improve the accuracy of diagnosis .%目的：通过对比准静态弹性成像三种诊断方法的诊断效能，找到最佳的诊断方法，提高诊断准确性。方法对523例（652个病灶）乳腺占位患者行常规超声及超声弹性成像检查，先用5分评分法联合常规超声得出诊断结论，然后测量病灶的面积比值及应变率比值，以病理结果作为参考标准，构建受试者操作特性曲线（ receiver－operating characteris－tic， ROC），得出判断乳腺良恶性病变的曲线下面积（ AUC），最佳截断值（ cutoff value ）。结果面积比值法和应变率比值法AUC及cutoff值分别为：0．850、1．43；0．907、3．35。5分法、面积比值法和应变率比值法敏感性、特异性、准确性分别为：96．23％、87．05％、88．65％；90．63％、78．81％、86．35％；92．31％、74．58％、85．59％。评分法、面积比值法、应变率比值法诊断准确性两两比较无统计学差异（ P ＞0．05）。结论5分法、面积比值法和应变率比值法诊断准确性无统计学差异，但各具优势，应视具体情况灵活运用，以提高诊断准确性。
展开▼
