目的：采用血氧水平依赖的脑功能磁共振成像技术（ BOLD－fMRI）技术，研究正常人欣赏欢快音乐时的脑功能区定位，探讨可能的神经网络调节机制。方法选择15例正常健康受试者，年龄25～50岁，在欣赏欢快音乐同时，用BOLD－fMRI技术进行脑功能磁共振成像检查，采用SPM软件对原始数据进行统计学处理，获得平均激活图，分析激活增高的脑区。结果15例受试者在欣赏欢快音乐时大脑显著激活了视觉注意网络、默认网络、运动感觉网络、认知记忆网络的相关脑区，这些脑区可能参与了音乐的感知、注意、记忆、情绪反应等过程。结论功能磁共振成像技术在音乐欣赏的功能定位方面具有独特的价值，欢快音乐欣赏可激活大脑多种功能神经网络参与处理。%Objective By using the blood oxygen level dependent functional magnetic resonance imaging ( BOLD-fMRI ) technique, to study the normal brain function localization when listening cheerful music , and then to explore the possible neural network adjustment mechanism .Methods We selected 15 volunteers with normal mental health , age between 25~50 .While listening the cheerful music , BOLD-fMRI examinations were performed and the original image data were obtained for statistical processing by using SPM software .And then, the average activation graph was analyzed to acquire the activated brain regions . Results While the subjects listening the cheerful music , several brain networks were activated including visual attention net-work, default mode network , sensorimoter network and cognitive network .These brain regions probably involved in the Music per-ception, attention, memory, and emotional reaction process .Conclusion The application of fMRI technique in music apprecia-tion has unique value in the respect of functional localization , cheerful music can activate the brain functions involved in several neural networks .
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