PCOS对女性健康影响的共识:ESHRE/ASRM在阿姆斯特丹发起的第三届PCOS共识研讨会(上)

摘要

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females,with a high prevalence.The etiology of this heterogeneous condition remains obscure,and its phenotype expression varies.Two consensus workshops focused on diagnosis (published in 2004) and infertility management(published in 2008),which previously sponsored by ESHRE/ASRM.Those consensuses are widely cited now.In the present third PCOS consensus report,all current knowledge was summarized,and some blind area on understanding the women's health of PCOS were clarified.The topics were addressed in a systematic fashion,including adolescence,hirsutism and acne,contraception,menstrual cycle abnormalities,life quality,ethnicity,pregnancy complications,long-term metabolic and cardiovascular health,and the risk of cancer.%多囊卵巢综合征(polycystic ovary syndrome,PCOS)是女性最常见的内分泌疾病.这种遗传异质性疾病的病因学尚不清楚,其表型表达各不相同.由欧洲人类生殖及胚胎学会/美国生殖医学会(ESHRE/ASRM)发起的分别针对其诊断(2004年)和不孕管理(2008年)的两个PCOS共识研讨会,正被广泛引用.目前第三届PCOS共识研讨会概述了当前已有的认识,也明确了关于PCOS对女性健康多方面影响的认识盲区.已研究的相关主题包括青春期问题、多毛症和痤疮、避孕、月经周期异常、生活质量、种族、妊娠并发症、远期代谢和心血管健康问题,以及最终的癌变风险.