精子纤维鞘发育不良行胞浆内单精子注射成功妊娠一例

摘要

The dysplasia of sperm fibrous sheath (DFS) is a rare disease that is characterized by severe abnormality of sperm movement and flagella morphology. The ultrastructure observation can find the typical abnormality of sperm fibrous sheath and axial filament assembly. We recently got a successful pregnancy of DFS by intracytoplasmic single sperm injection (ICSI). In this case, the sperm selected by HOST method was used in ICSI.%精子纤维鞘发育不良(DFS)是一类罕见病,表现为严重的精子运动障碍和精子鞭毛形态异常,超微结构显示精子纤维鞘及轴丝组装异常.最近,本中心通过低渗肿胀试验(HOST)选择精子进行胞浆内单精子注射(ICSI)治疗患者1例,获得成功妊娠.