二次OGTT诊断妊娠期糖尿病围生结局分析

摘要

目的:探讨二次口服葡萄糖耐量试验(oral glucose tolerance test,OGTT)诊断妊娠期糖尿病(gestational diabetes mellitus,GDM)的围生结局.方法:初次OGTT诊断GDM者188例,作为GDM1组.二次OGTT诊断GDM者38例,作为GDM2组;同期血糖正常产妇200例,作为对照组.比较3组产妇围生结局,如产后出血、早产、胎膜早破、巨大儿等.结果:GDM2组的产后出血、胎膜早破、大于胎龄儿发生率高于对照组,差异有统计学意义(P＜0.05);GDM2组的巨大儿发生率高于GDM1组,差异有统计学意义(P＜0.05).结论:二次OGTT可以提高GDM的诊断率,从而尽早诊断、积极干预GDM,改善妊娠结局.%Objective:To research the perinatal outcomes of the gestational diabetes mellitus (GDM) women who were diagnosed by repeated oral glucose tolerance test (OGTT) examinations.Methods:188 women were diagnosed GDM by preliminary OGTT examinations as GDM1 group,38 women were diagnosed GDM by repeated OGTT examinations as GDM2 group,and 200 pregnant women with normal blood glucose as control group.Compared 3 groups' perinatal outcomes,such as postpartum hemorrhage,preterm labour,PROM,macrosomia.Results:GDM2 group had significantly more postpartum hemorrhage,PROM,large for gestational age fetus than control group (P＜0.05).GDM2 group had more macrosomia than GDM1 group,the difference had statistic significance (P＜0.05).Conclusions:Repeated OGTT examinations can improve the GDM diagnosis ratio,so that we can early diagnose and actively intervene GDM,and improve pregnancy outcomes.