胃康合剂对食管静脉曲张套扎术后门脉高压性胃病的影响

摘要

目的 探讨胃康合剂对食管静脉曲张套扎术后门脉高压性胃病的影响.方法 选取2013年1月至2015年1月在我院住院接受食管静脉曲张套扎术的患者共76例,将患者随机分成2组,每组38例,对照组予以套扎术治疗,治疗组套扎术后给予胃康合剂口服治疗,对其术前、术后门脉高压性胃病(poral hypertensive gastropathy,PHG)的程度进行对比分析.结果 对照组术后无论是1周还是1个月后对PHG都有显著影响(P<0.05),造成新增PHG或者PHG程度的加重,而治疗组术前与术后(1周及1个月)比较,PHG无显著差异(P>0.05).两组间比较,术后1周及1个月PHG演进(按照新增的PHG和加重的PHG数)差异均具有统计学意义(P<0.05).结论 食管静脉曲张单纯内镜套扎治疗在短期内会加重PHG的严重程度,而胃康合剂能减少食管静脉曲张套扎术后PHG的发生及发展.%Objective To investigate the effects of Weikang mixture on portal hypertensive gastropathy (PHG) after esophageal varice ligation. Methods A total of 76 cases patients with esophageal variceal ligation in our hospital from January 2013 to January 2015 were randomly divided into 2 groups, 38 cases in each group. The control group was received ligation, the treatment group was administrated with Weikang mixture, the preoperative PHG degree and postoperative PHG degree were compared. Results The control group after treatment for one week and one month has significant effect on PHG (P<0.05), which newly caused PHG or aggravateed the degree of PHG. PHG in the treatment had no significant difference before and after treatment (P>0.05). The differences of PHG between the two groups were statistically significant (P<0.05). Conclusion The pure esophageal varice ligation could increase the severity of PHG, and Weikang mixture could reduce the occurrence and development of PHG after esophageal varice ligation.