ABSTRACT:Objective To explore the diagnostic value of ultrasound-guided transbronchial needle aspiration in advanced stage lung cancer with anterior mediastinal lymphadenectasis. Methods Twenty-seven cases with anterior mediastinal lymphadenectasis not yet obtained pathologic diagnosis by bronchoscopy and repeated examination of sputum castoff cells were analyzed.Results Pathologic diagnosis was made in all patients,including squamous-celled carcinoma 9 cases,adenocarcinoma 11 cases,small cell carcinoma 6 cases,anaplastic carcinoma 1 case.None of the patients suffered from complications such as mediastinal emphysema, pneumothorax,or hemorrhage.Conclusion Ultrasound-guided transbronchial needle aspiration is a safe,accurate,dependable,economy and facility diagnostic method for some advanced stage lung cancer with anterior mediastinal lymphadenectasis.%目的：探讨彩色超声引导针吸活检术在晚期肺癌伴前纵隔淋巴结肿大诊断中的应用。方法对肺部肿块伴纵隔淋巴结肿大、支气管镜检查及反复痰脱落细胞检查未取得病理诊断的27例患者行彩超引导下前纵隔淋巴结穿刺活检。结果全部患者获得病理诊断结果，鳞状细胞癌9例，腺癌11例，小细胞肺癌6例，未分化癌1例。未发生气胸、纵隔气肿、穿刺部位出血及感染等常见并发症。结论超声引导针吸活检术在晚期肺癌伴前纵隔淋巴结肿大诊断中具有安全、准确、可靠、经济、易于开展的应用价值。
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