Effect of gestational diabetes on the fetal fat metabolism

摘要

Objective: To explore the differences of insulin, leptin, umbilical blood sugar, and adiponectin levels among the pregnant women receiving gestational diabetes treatment, not receiving gestational diabetes treatment, and the pregnant women with mild gestational diabetes. Methods: A total of 120 pregnant women with gestational diabetes who were admitted in our hospital from May, 2011 to July, 2012 were included in the study and randomized into three groups, i.e. gestational diabetes group, gestational diabetes control group, and gestational diabetes treatment group, with 40 cases in each group. The pregnant women in the three groups were given routine care. On the basis of routine care, the pregnant women in the treatment group were given blood sugar monitoring and diet control, and insulin treatment was provided if necessary. Then the insulin, leptin, umbilical blood sugar, and adiponectin levels in the three groups were detected. Results: The leptin level in the diabetes group was significantly higher than that in the control group and the treatment group (P0.05). The blood sugar levels after breakfast, lunch, and dinner in the treatment group and control group were significantly lower than those in the diabetes group (P<0.05). The blood sugar levels after breakfast, lunch, and dinner in the control group were significantly lower than those in the treatment group (P<0.05). Conclusions: Gestational diabetes can give rise to a certain effect on the fetal fat metabolism by altering the leptin, blood sugar, and adiponectin levels. The related treatment on the patients can effectively control this alteration, enhance the clinical efficacy, and deserve a wide recommendation.