Assessment of the intraoperative wound degree as well as postoperative immune function and ventilation function of plasma radiofrequency ablation for the treatment of adenoid hypertrophy

摘要

Objective:To study the intraoperative wound degree as well as postoperative immune function and ventilation function of plasma radiofrequency ablation for the treatment of adenoid hypertrophy.Methods: A total of 118 children with adenoid hypertrophy who underwent surgical treatment in our hospital between May 2013 and April 2016 were selected and divided into the control group (n=59) who accepted conventional endoscopic cutting aspirator and the observation group (n=59) who accepted the plasma radiofrequency ablation according to the single-blind randomized controlled method. Before and after operation, the levels of peripheral blood trauma-related indexes, humoral immunity and complement indexes as well as nasal ventilation function indexes were determined.Results:Before operation, the differences in trauma-related indexes, humoral immunity and complement indexes as well as nasal ventilation function indexes were not statistically significant between two groups of children. Immediately after operation, the peripheral blood SP, PGE2 and CRP contents of observation group were lower than those of control group; 24 h after operation, peripheral blood IgG, IgM, IgA, C3 and C4 contents of observation group were lower than those of control group; 1 week after operation, TIR and TER levels of observation group were lower than those of control group while NPV and MCSA levels were higher than those of control group.Conclusion:Plasma radiofrequency ablation for treatment of adenoid hypertrophy causes smaller intraoperative wound and has more advantages in optimizing the body's immune function and ventilation function.