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外文期刊>海南医科大学学报(英文版)
>Effect of insulin in combined with Chinese medicine formulae on the serum Mg2+ and visfatin levels, maternal and infant outcome in pregnant women with gestational diabetes mellitus
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Effect of insulin in combined with Chinese medicine formulae on the serum Mg2+ and visfatin levels, maternal and infant outcome in pregnant women with gestational diabetes mellitus
Objective:To explore the effect of insulin in combined with Chinese medicine formulae on the serum Mg2+ and visfatin levels, maternal and infant outcome in pregnant women with gestational diabetes mellitus (GDM).Methods:A total of 108 pregnant women with GDM who were admitted in our hospital were included in the study and randomized into the observation group (n=55) and the control group (n=53). The patients in the two groups were given diet control, exercise therapy, and subcutaneous injection of insulin. On this basis, the patients in the observation group were given self-made Chinese medicine formulae, continuously for 2 weeks. The blood sugar level, and serum Mg2+ and visfatin (VF) levels before treatment and before delivery in the two groups were detected. The maternal and infant outcome in the two groups was evaluated.Results:The serum HbA1c, FPG, 1 h PBG, 2 h PBG, and VF levels before delivery in the two groups were significantly reduced when compared with before treatment (P<0.05), while the serum Mg2+ level was significantly elevated when compared with before treatment (P<0.05). The improvement of the above indicators before delivery in the observation group was more significant when compared with the control group (P<0.05). The occurrence rate of cesarean section, premature delivery, gestational hypertension, fetal distress, and macrosomia in the observation group was significantly lower than that in the control group (P<0.05).Conclusions:Insulin in combined with self-made Chinese medicine formulae can effectively control the blood sugar level in pregnant women with GDM, and improve the maternal and infant outcome.
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机译:目的:探讨胰岛素联合中药复方对妊娠糖尿病(GDM)孕妇血清Mg2 +和visfatin水平,母婴结局的影响。方法:共收治108例GDM孕妇。将我院的患者纳入研究并随机分为观察组(n = 55)和对照组(n = 53)。两组患者均接受饮食控制,运动疗法和皮下注射胰岛素。在此基础上,观察组患者连续2周服用自制的中药配方。检测两组在治疗前和分娩前的血糖水平以及血清Mg2 +和visfatin(VF)水平。结果:两组分娩前的血清HbA1c,FPG,1 h PBG,2 h PBG和VF水平较治疗前明显降低(P <0.05)。 ,而治疗前的血清Mg2 +水平显着升高(P <0.05)。与对照组相比,观察组上述指标在分娩前的改善更为显着(P <0.05)。观察组剖宫产,早产,妊娠高血压,胎儿窘迫和巨大儿的发生率明显低于对照组(P <0.05)。结论:胰岛素结合自制中药配方可以有效控制GDM孕妇的血糖水平,并改善母婴结局。
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