分别采用0.5%、10%、20%、40%、100%(质量比)丙三醇缩水甘油醚(GPE)交联脱细胞猪真皮基质(pADM),检测交联前后材料的亲水性能.研究结果表明,随着交联剂GPE用量的增加,材料的收缩温度逐渐提高,接触角明显降低;电镜扫描图显示交联后材料的孔隙有缩小的趋势,并导致了吸湿率和溶胀率的逐渐下降;红外图谱表明交联后材料的醚键增加,XPS图谱拟合发现含氧量增加.这些极性基团的增加,促进了保水率的升高,从而使GPE交联后材料的亲水性能提高.%Porcine acellular dermal matrix (pADM) was crosslinked by serial dosage 0,5％, 10％, 20％, 40％,100％ (wt) of glycerol polyglycidyl ether (GPE). The properties of them were characterized with Ts,hygroscopicity, rate of absorbed water, water retentivity, contact angel, FT-IR, XPS and SEM before and after crosslinked. With the increase of GPE concentration, Ts of GPE-pADM was enhanced obviously. The holes of GPE-pADM tended to shrink after crosslinked from the SEM image of the material surface,and it resulted in the fall of the rate of absorbed water and hygroscopicity. Improvement of surface hydrophilicity was proved by the decline of contact angle in the surface of GEP-pADM. The added polar bond, aliphatic ether bond and C—O bond,were discovered by the shape (about 1083cm-1) change of IR spectroscopy curves and the increase of content of oxygen were observed by XPS, consistent with the principle of GPE crosslink reaction, which was the result of increasement of combined water and hydrophilicity. These proved that hydrophilicity of pADM was increased after crosslinked by GPE.
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