一种双邻苯二酚类衍生物的合成与螯合性能研究

摘要

In order to get a uranyl ligand with high efficiency,low toxicity and selectivity,a bis(catecholamine) ligand was synthesized by incorporating the catecholamine chelate moiety into molecular scaffolds with flexible alkyl chain and β-diketone.The structure of the synthesized compounds was characterized by FT-IR,1H NMR,13C NMR and APCI-MS.The chelating properties of the ligand with UO22+,Cu2+ and Zn2+ ions were investigated by spectrophotometric titration and potentiometric titration techniques.The results indicated that the bis (catecholamine) ligand has effective binding ability with UO2 2+ and Cu2+,but weak bingding ability with Zn2+.Its pM values are 20.98,15.14 and 7.31,respectively,which indicated that the bis(catecholamide) ligand has a selective binding ability with UO22+ and can be a potential decorporation agent in future.%为获得具有高效率、低毒性以及选择性的铀酰配体,采用邻苯二酚配位单元拼接柔性烷基链β-二酮分子骨架,合成了一种双邻苯二酚配体.目标化合物结构经FT-IR、1 H NMR、1 3C NMR及APCI-MS确证.采用光谱滴定和电位滴定法研究了其对UO22+、Cu2+和Zn2+的螯合性能.结果显示,该配体与UO22+和Cu2+有较好的络合能力,同时与Zn2+络合能力较弱,其pM值分别为20.98,15.14,7.31,表明该配体对UO22+具有一定的选择性络合能力,有望成为一种潜在的促排剂.