小剂量静脉应用甲氧氯普胺治疗急性胃肠炎患儿呕吐急症的疗效

摘要

Objective To investigate the clinical efficacy and safety of low-dose metoclopramide injection for treating acute gastroenteritis of frequent vomiting children. Methods One hundred and twenty cases of acute gastroenteritis of frequent vomiting children in the emergency department of our hospital from February 2012 to January 2013 were randomly divided into the treatment group and the control group, 60 cases in each group. The treatment group was treated with low-dose motoclopramide injection.Results The total effective rate was 100% in the treatment group and significantly higher than 83.33% in the control group with statistical difference between the two groups.Conclusion The clinical efficacy of low-dose metoclopramide injection for treating acute gastroenteritis is rapid and good without significant adverse reactions.%　　目的探讨小剂量静脉应用甲氧氯普胺治疗以频繁呕吐而无法口服给药为主要表现的急性胃肠炎的临床疗效。方法选择2012年2月～2013年3月本院儿科急诊就诊的频繁呕吐的急性胃肠炎患儿120例，随机将患儿分为治疗组60例和对照组60例。均给予补液、护胃、止泻等常规治疗，治疗组在对照组基础上静脉应用甲氧氯普胺治疗，比较两组疗效。结果治疗组总有效率为100%，对照组为83.33%，差别有统计学意义（P均<0.01）。结论小剂量静脉应用甲氧氯普胺治疗急性胃肠炎频繁呕吐效果明显，不良反应小。