Objective To evaluate the function of segments of left ventricular wall in patients with coronary heart disease and its correlation with exercise electrocardiography by real—time three—dimensional ecbocardiography (RT — 3DE). Methods Thirty healthy persons and 30 patients with coronary heart disease were enrolled in this study. The stroke volume (regional stroke volume, rSV) .end diastolic volume (rEDV), regional radio segment rate ( rEF) of 17 segments of left ventricular wall were measured by real-time three —dimensional echocardiography. And all subjects underwent treadmill exercise test. Results The real-time three-dimensional images with clear endocardia! border and 3.7 scgmental volume—time curves were obtained in both groups. Significant differences were found in rSV,rEDV,rPEF values of 17 segments between the two groups (P＜0.05). The segmental function in patients with coronary heart disease and ST segment changes from positive exercise stress test were highly correlated(P＜0. 05). Conclusion There is significant difference in left ventricular systolic function between patients with coronary heart disease and health control. The quantitative real —time three —dimensional echocardiography for the evaluation of left ventricular systolic dysfunction and treadmill exercise test in the detection of coronary artery disease are highly correlated,%目的 应用实时三维超声心动图(RT-3DE)评价冠心病患者左心室壁节段功能及其与运动心电图的相关性.方法 冠心病组患者30 例,30 例健康者为对照组,RT-3DE 分别测量其左室壁17 节段的节段每搏量(rSV)、舒张末容积(rEDV)及节段射血率(rPEF),所有受检者进行平板运动试验.结果 两组均获得具有清晰内膜边界的实时三维图像和17 节段容积-时间曲线;两组间17 节段rSV、rEDV、rPEF 测值间差异有统计学意义(P﹤0.05);冠心病患者的节段功能与平板运动试验阳性的ST 段改变高度相关(P﹤0.05).结论 冠心病患者与健康成人左室壁节段收缩功能存在差异,RT-3DE定量评价左室壁节段收缩功能异常与平板运动试验阳性对冠心病的检测高度相关.
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